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甲氧基聚乙二醇双十四烷基乙酰胺

甲氧基聚乙二醇双十四烷基乙酰胺

产品简称:ALC-0159(mPEG-DTA)CAS no.:1849616-42-7
分子量:2K, 5K, 10K, 20K, 40K包装尺寸:1g, 5g, 10g, 100g, 1kg, 10kg储存:-20±5℃
CAS no. 分子量(Mp) 产品编码
  2,000 06020112302
5,000 06020112306
10,000 06020112309
20,000 06020112312
30,000 06020112313
40,000 06020112315


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相关文献:

1. Nguyen CM, Vu TT, Nguyen MN, et al. Neoantigen-d mRNA vaccine exhibits superior anti-tumor activity compared to synthetic long peptides in an in vivo lung carcinoma model. Cancer Immunol Immunother. 2025;74(4):145. Published 2025 Mar 12. doi:10.1007/s00262-025-03992-7
2. Liu S, Wen Y, Shan X, et al. Charge-assisted stabilization of lipid nanoparticles enables inhaled mRNA delivery for mucosal vaccination. Nat Commun. 2024;15(1):9471. Published 2024 Nov 2. doi:10.1038/s41467-024-53914-x
3. Li M, Zheng X, Yu X, et al. Potentiating the Efficacy of mRNA Vaccines through NIR-II Imaging-Guided Precise Vaccination. Adv Sci (Weinh). 2025;12(37):e13014. doi:10.1002/advs.202413014
4. Kim S, Jeon JH, Kim M, et al. Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site. Nat Commun. 2024;15(1):7226. Published 2024 Aug 27. doi:10.1038/s41467-024-51411-9
5. Liu D, Wang X, Xu L, et al. Screening lipid nanoparticles using DNA barcoding and qPCR. Colloids Surf B Biointerfaces. 2025;251:114598. doi:10.1016/j.colsurfb.2025.114598
6. Hassanel DNBP, Pilkington EH, Ju Y, Kent SJ, Pouton CW, Truong NP. Replacing poly(ethylene glycol) with RAFT lipopolymers in mRNA lipid nanoparticle systems for effective gene delivery. Int J Pharm. 2024;665:124695. doi:10.1016/j.ijpharm.2024.124695
7. Tao Y, Tian C, Qi S, et al. Targeting both death and paracaspase domains of MALT1 with antisense oligonucleotides overcomes resistance to immune-checkpoint inhibitors. Nat Cancer. 2025;6(4):702-717. doi:10.1038/s43018-025-00930-5
8. Yang K, Bai B, Li X, et al. Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy. Sci Adv. 2025;11(9):eadn7256. doi:10.1126/sciadv.adn7256
9. Wang Y, Luo G, Wang H, et al. Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-d nanoparticles. Nat Commun. 2025;16(1):5964. Published 2025 Jul 1. doi:10.1038/s41467-025-60962-4
10. Sui, Meihua & Wang, Yisha & Luo, Gan & Wang, Haiyang & Zheng, Yue & Zhou, Wenbin & Lin, Junrong & Chen, Baocheng. (2024). Construction and Application of a Technical Platform for Determining Cell Cycle- and Autophagy-Associated Cellular Uptake of Lipid-d Nanoparticles. 10.21203/rs.3.rs-3974581/v1.
11. Wang H, Wang Y, Yuan C, et al. Polyethylene glycol (PEG)-associated immune responses triggered by clinically relevant lipid nanoparticles in rats. NPJ Vaccines. 2023;8(1):169. Published 2023 Nov 2. doi:10.1038/s41541-023-00766-z

12. Men J, Zhang X, Zhang W, Gao X, Cheng M, Yu X, Qi S. Synergistic inhibition of exosome secretion and PD-L1 silence via a functional supramolecular lipid nanoparticle to boost antitumor immunity. J Control Release. 2026;399(Pt A):115331. doi:10.1016/j.jconrel.2026.115331

13. Zhou H, Sun Y, Zhang L, Liang X, Bai J, Gao Y, Jiang P. An mRNA vaccine encoding multiple envelope glycoproteins of porcine reproductive and respiratory syndrome virus confers efficient protection against NADC30-like strains. Int J Biol Macromol. 2026 Jan;339(Pt 2):149888. doi: 10.1016/j.ijbiomac.2025.149888. Epub 2025 Dec 23. PMID: 41448308.

14. Handa K, Kawamura M, Sasai M, Matsuzaki T, Harada A, Fujimura L, Whitehouse J, Saito S, Komukai S, Kitamura T, Fujishiro A, Hirano K, Miki K, Miyagawa S. Effective transcatheter intracoronary delivery of mRNA-lipid nanoparticles targeting the heart. J Control Release. 2025 May 10;381:113623. doi: 10.1016/j.jconrel.2025.113623. Epub 2025 Mar 10. PMID: 40073941.

15. Jiang L, Zhou W, Liu F, Li W, Xu Y, Liang Z, Cao M, Hou L, Liu P, Wu F, Shen A, Zhang Z, Zhang X, Zhao H, Pan X, Wu T, Jia W, Zhang Y. An mRNA Vaccine for Herpes Zoster and Its Efficacy Evaluation in Naïve/Primed Murine Models. Vaccines (Basel). 2025 Mar 19;13(3):327. doi: 10.3390/vaccines13030327. PMID: 40266224; PMCID: PMC11946168.

16. Nguyen CM, Vu TT, Nguyen MN, Tran-Nguyen TS, Huynh CT, Ha QT, Nguyen HN, Tran LS. Neoantigen-based mRNA vaccine exhibits superior anti-tumor activity compared to synthetic long peptides in an in vivo lung carcinoma model. Cancer Immunol Immunother. 2025 Mar 12;74(4):145. doi: 10.1007/s00262-025-03992-7. PMID: 40072566; PMCID: PMC11949242.

17. Zhang J, Li Y, Zeng F, Mu C, Liu C, Wang L, Peng X, He L, Su Y, Li H, Wang A, Feng L, Gao D, Zhang Z, Xu G, Wang Y, Yue R, Si J, Zheng L, Zhang X, He F, Yi H, Tang Z, Li G, Ma K, Li Q. Virus-like structures for combination antigen protein mRNA vaccination. Nat Nanotechnol. 2024 Aug;19(8):1224-1233. doi: 10.1038/s41565-024-01679-1. Epub 2024 May 27. PMID: 38802667; PMCID: PMC11329372.

关键词:Methoxypoly(ethylene glycol)-ditetradecylacetamidemPEG-DTA2-[(polyethylene glycol)-2000]-NN-ditetradecylacetamidePrizer、Moderna新冠疫苗辅料
甲氧基聚乙二醇双十四烷基乙酰胺
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